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Mitochondria are closely linked to aging over time, mitochondrial function typically declines, contributing to reduced energy, loss of muscle, and increased metabolic disorders in older adults

Combination therapy may exert synergistic effects of drugs, improve treatment efficacy, and reduce the occurrence of adverse reactions

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As such, measuring MDA, 8-OHdG,and R-SH levels provides a quantitative and qualitative assessment of oxidative stress, providing clinicians with a valuable tool in the diagnostic armamentarium for IBD